Document Detail

Promoting shorter duration of ventilator treatment decreases the number of painful procedures in preterm infants.
MedLine Citation:
PMID:  19650835     Owner:  NLM     Status:  MEDLINE    
AIM: To investigate whether promoting shorter ventilator treatment decreases the number of painful procedures and the use of analgesics in preterm infants. METHODS: Retrospective patient chart review of all preterm infants in one Neonatal Intensive Care Unit (NICU) was carried out in 2000 (n = 240) and 2005 (n = 206). Between these cohorts, early nasal continuous positive airway pressure (nCPAP) application and early extubation policy were introduced. RESULTS: Fewer infants were intubated (22 vs. 32%, p = 0.03), the duration of ventilator treatment decreased (6.7 SD 11.3 vs. 9.0 SD 11.1 days, p < 0.001) and nCPAP treatment became more common (41 vs. 25%, p < 0.001) in 2005 than in 2000. Similarly, the infants' exposure to painful procedures did not decrease significantly (61.9 SD 98.5 vs. 67.1 SD 104.3 procedures, p = 0.32) but the procedures related to respiratory support were fewer (45.2 SD 79.5 vs. 68.9 SD 91.1 procedures, p < 0.001) in 2005 than in 2000. In addition, the amount of pain medication used was significantly lower in 2005 than in 2000. One day on a ventilator included more painful procedures than a day on nCPAP (11.2 95% CI: 11.0-11.5 vs. 4.2 95% CI: 4.1-4.4 procedures, p < 0.001) during both study years. CONCLUSION: Early nCPAP and early extubation policies were successfully implemented in an NICU resulting in less invasive respiratory support. This was associated with fewer painful procedures and less pain medication in the preterm infants who required respiratory support. Despite this positive effect, the number of painful procedures in all preterm infants stayed at the same level. Our results provide further support for the use of nCPAP in preterm infants.
A Axelin; U Ojajärvi; J Viitanen; L Lehtonen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-07-24
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  98     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-07     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1751-5     Citation Subset:  IM    
Department of Nursing Science, University of Turku, Turku, Finland.
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MeSH Terms
Analgesics / administration & dosage*
Chi-Square Distribution
Cohort Studies
Continuous Positive Airway Pressure / methods*
Infant, Newborn
Infant, Premature*
Intensive Care, Neonatal / methods*
Intubation, Intratracheal / methods*
Pain Measurement
Regression Analysis
Retrospective Studies
Time Factors
Treatment Outcome
Ventilator Weaning
Ventilators, Mechanical
Reg. No./Substance:

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