| Promoting shorter duration of ventilator treatment decreases the number of painful procedures in preterm infants. | |
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MedLine Citation:
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PMID: 19650835 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To investigate whether promoting shorter ventilator treatment decreases the number of painful procedures and the use of analgesics in preterm infants. METHODS: Retrospective patient chart review of all preterm infants in one Neonatal Intensive Care Unit (NICU) was carried out in 2000 (n = 240) and 2005 (n = 206). Between these cohorts, early nasal continuous positive airway pressure (nCPAP) application and early extubation policy were introduced. RESULTS: Fewer infants were intubated (22 vs. 32%, p = 0.03), the duration of ventilator treatment decreased (6.7 SD 11.3 vs. 9.0 SD 11.1 days, p < 0.001) and nCPAP treatment became more common (41 vs. 25%, p < 0.001) in 2005 than in 2000. Similarly, the infants' exposure to painful procedures did not decrease significantly (61.9 SD 98.5 vs. 67.1 SD 104.3 procedures, p = 0.32) but the procedures related to respiratory support were fewer (45.2 SD 79.5 vs. 68.9 SD 91.1 procedures, p < 0.001) in 2005 than in 2000. In addition, the amount of pain medication used was significantly lower in 2005 than in 2000. One day on a ventilator included more painful procedures than a day on nCPAP (11.2 95% CI: 11.0-11.5 vs. 4.2 95% CI: 4.1-4.4 procedures, p < 0.001) during both study years. CONCLUSION: Early nCPAP and early extubation policies were successfully implemented in an NICU resulting in less invasive respiratory support. This was associated with fewer painful procedures and less pain medication in the preterm infants who required respiratory support. Despite this positive effect, the number of painful procedures in all preterm infants stayed at the same level. Our results provide further support for the use of nCPAP in preterm infants. |
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Authors:
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A Axelin; U Ojajärvi; J Viitanen; L Lehtonen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-07-24 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 98 ISSN: 1651-2227 ISO Abbreviation: Acta Paediatr. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-07 Completed Date: 2009-12-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 1751-5 Citation Subset: IM |
Affiliation:
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Department of Nursing Science, University of Turku, Turku, Finland. anna.axelin@utu.fi |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analgesics
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administration & dosage* Chi-Square Distribution Cohort Studies Continuous Positive Airway Pressure / methods* Female Humans Infant, Newborn Infant, Premature* Intensive Care, Neonatal / methods* Intubation, Intratracheal / methods* Male Pain Measurement Regression Analysis Retrospective Studies Time Factors Treatment Outcome Ventilator Weaning Ventilators, Mechanical |
| Chemical | |
Reg. No./Substance:
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0/Analgesics |
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