Document Detail


Prominent perivenular spaces in multiple sclerosis as a sign of perivascular inflammation in primary demyelination.
MedLine Citation:
PMID:  16219839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, we describe prominent perivenular spaces as a sign that is seen on high-resolution (512 x 512) transverse T2-weighted MR images in patients with multiple sclerosis. The observed widening of perivenular space is depicted as a stringlike hyperintensity projecting radially and aligned with multiple sclerosis lesions (usually small), following the course and configuration of deep venular structures. This widening may be an important sign in differentiating primary (ie, in multiple sclerosis) from secondary causes of demyelination.
Authors:
Yulin Ge; Meng Law; Joseph Herbert; Robert I Grossman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  26     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-12     Completed Date:  2005-11-21     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2316-9     Citation Subset:  IM    
Affiliation:
Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / blood supply*
Demyelinating Diseases / diagnosis,  pathology*
Diagnosis, Differential
Female
Humans
Inflammation
Magnetic Resonance Imaging*
Middle Aged
Multiple Sclerosis, Relapsing-Remitting / pathology*
Venules / pathology*
Grant Support
ID/Acronym/Agency:
M01 RR00096/RR/NCRR NIH HHS; R37 NS 29029-11/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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