| Prominent Degos-like skin lesions in a patient with chronic cutaneous lupus erythematosus. | |
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MedLine Citation:
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PMID: 20673533 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Malignant atrophic papulosis, commonly known as Degos disease, is a rare vasculopathy encompassing both benign, cutaneous and lethal systemic variants. We report a case of chronic cutaneous lupus erythematosus in a 41-year-old male presenting with prominent Degos-like skin lesions. Multiple atrophic, porcelain-white, scar-like papules and plaques with dusky, erythematous borders, suggestive of malignant atrophic papulosis, were noted on the patient's back. Additional cutaneous findings included photo-distributed facial erythema and discoid lupus-like plaques on the face, shoulders, and arms. Clinicopathological correlation supported a diagnosis of chronic cutaneous lupus erythematosus; hydroxychloroquine was initiated with good clinical response. No new or active lesions were observed at the sixteen-month follow-up. This case highlights a rare skin finding associated with chronic cutaneous lupus erythematosus and underscores the importance of ruling out primary autoimmune disease, particularly lupus, before a diagnosis of malignant atrophic papulosis can be made. |
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Authors:
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Misha M Mutizwa; Mark B Tang; See Ket Ng |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-07-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 16 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-11-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 5 Citation Subset: IM |
Affiliation:
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Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, USA. mmutizwa@dom.wustl.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antirheumatic Agents / therapeutic use Aspirin / therapeutic use Diagnosis, Differential Humans Hydroxychloroquine / therapeutic use Lupus Erythematosus, Discoid / complications, diagnosis*, drug therapy, pathology Male Malignant Atrophic Papulosis / complications, diagnosis*, drug therapy, pathology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antirheumatic Agents; 118-42-3/Hydroxychloroquine; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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