| Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens). | |
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MedLine Citation:
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PMID: 19906819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Botanicals have numerous health benefits. Here, we used the Mexican fruit fly to screen 14 compounds and botanicals for their prolongevity effects and found an oregano and cranberry mixture (OC) improved survival. We then evaluated prolongevity effects of OC within the context of diet composition. Individual flies were fed 0%, 1%, or 2% OC in one of the three diets containing sugar and yeast extract (SY) at a ratio of 3:1, 9:1, or 24:1. We found that prolongevity effects of OC depended upon dose, gender, and diet composition. The greatest increase in longevity was observed in females fed the SY24:1 diet with 2% OC compared to the non-supplemented diet. OC did not reduce egg laying and, hence, did not compromise fecundity under any dietary condition tested here. This study reveals the prolongevity effects of OC and supports the emerging view that benefits of botanicals on aging depend on diet composition and gender. |
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Authors:
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Sige Zou; James R Carey; Pablo Liedo; Donald K Ingram; Binbing Yu; Reza Ghaedian |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't Date: 2009-11-11 |
Journal Detail:
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Title: The journals of gerontology. Series A, Biological sciences and medical sciences Volume: 65 ISSN: 1758-535X ISO Abbreviation: J. Gerontol. A Biol. Sci. Med. Sci. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-23 Completed Date: 2010-01-15 Revised Date: 2013-05-31 |
Medline Journal Info:
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Nlm Unique ID: 9502837 Medline TA: J Gerontol A Biol Sci Med Sci Country: United States |
Other Details:
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Languages: eng Pagination: 41-50 Citation Subset: AIM; IM |
Affiliation:
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Functional Genomics Unit, Laboratory of Experimental Gerontology, National Institute on Aging, 251 Bayview Boulevard, Baltimore, MD 21224, USA. zous@grc.nia.nih.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Appetitive Behavior / physiology* Diet Female Longevity / drug effects*, physiology Male Origanum* Plant Extracts / pharmacology* Tephritidae / growth & development* Vaccinium macrocarpon* |
| Grant Support | |
ID/Acronym/Agency:
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P01-AG022500-01/AG/NIA NIH HHS; P01-AG08761-10/AG/NIA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Plant Extracts |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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