Document Detail


Prolonged treatment interruption in chronic HIV infection: a new strategy?
MedLine Citation:
PMID:  15668548     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The introduction of highly active antiretroviral therapy in 1995 dramatically decreased AIDS-related events and deaths rates; however, the enthusiasm among the medical and social community was soon limited by the growing incidence of various side-effects that often greatly limited patients' quality of life. The second problem caused by such a complex treatment consisted of sub-optimal adherence, with a consequent higher risk of the development of drug resistance.
Authors:
Riccardo Giuntini; Canio Martinelli; Silvia Ambu; Dario Bartolozzi; Alberto Farese; Vieri Boddi; Francesco Leoncini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AIDS (London, England)     Volume:  19     ISSN:  0269-9370     ISO Abbreviation:  AIDS     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-25     Completed Date:  2005-09-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-11     Citation Subset:  IM; X    
Affiliation:
Infectious Diseases Unit, AOU Careggi, Florence, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiretroviral Therapy, Highly Active / adverse effects,  methods*
CD4 Lymphocyte Count
Chronic Disease
Cohort Studies
Didanosine / administration & dosage
Drug Administration Schedule
Female
HIV Infections / drug therapy*
HIV Protease Inhibitors / administration & dosage
Humans
Male
Middle Aged
RNA, Viral / analysis
Reverse Transcriptase Inhibitors / administration & dosage
Viral Load
Zidovudine / administration & dosage
Chemical
Reg. No./Substance:
0/HIV Protease Inhibitors; 0/RNA, Viral; 0/Reverse Transcriptase Inhibitors; 30516-87-1/Zidovudine; 69655-05-6/Didanosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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