Document Detail

Prolonged succinylcholine-induced paralysis in organophosphate insecticide poisoning.
MedLine Citation:
PMID:  2432808     Owner:  NLM     Status:  MEDLINE    
A case of prolonged succinylcholine-induced paralysis in a child with organophosphate insecticide poisoning is presented. Three hours and 15 minutes of apnea after the administration of succinylcholine was attributed to a decreased rate of succinylcholine metabolism from inhibition of pseudocholinesterase by the insecticide. Only one similar case has been reported previously in the English medical literature. If succinylcholine is to be used in patients with organophosphate poisoning, a prolonged paralysis should be anticipated.
B S Selden; S C Curry
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  16     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-02-17     Completed Date:  1987-02-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-7     Citation Subset:  AIM; IM    
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MeSH Terms
Apnea / chemically induced
Child, Preschool
Chlorpyrifos / poisoning*
Cholinesterases / blood
Paralysis / chemically induced*
Pralidoxime Compounds / therapeutic use
Succinylcholine / adverse effects,  metabolism,  therapeutic use*
Reg. No./Substance:
0/Pralidoxime Compounds; 2921-88-2/Chlorpyrifos; 306-40-1/Succinylcholine; 6735-59-7/pralidoxime; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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