| Prolonged refractory status epilepticus related to thrombotic thrombocytopenic purpura. | |
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MedLine Citation:
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PMID: 18351471 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is an extremely rare cause of status epilepticus. Review of literature demonstrated only four cases of brief status epilepticus (SE) associated with TTP. CASE: We describe a young woman with yet incomplete neurological recovery after prolonged refractory status epilepticus. Management required pentobarbital-induced coma for 60 days. Five months after onset, she was conversant and oriented with continued neuromuscular deficits. CONCLUSIONS: This is an unusual presentation of severe refractory SE associated with TTP. With aggressive life support and prolonged pentobarbital infusion, however, survival and the chance of meaningful recovery appear to be possible. |
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Authors:
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Alexander Y Zubkov; Alejandro A Rabinstein; Edward M Manno; Eelco F M Wijdicks |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Neurocritical care Volume: 9 ISSN: 1541-6933 ISO Abbreviation: Neurocrit Care Publication Date: 2008 |
Date Detail:
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Created Date: 2008-10-31 Completed Date: 2009-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101156086 Medline TA: Neurocrit Care Country: United States |
Other Details:
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Languages: eng Pagination: 361-5 Citation Subset: IM |
Affiliation:
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Department of Neurology, Division of Critical Care Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Escherichia coli Infections / complications Female Food Microbiology Humans Prognosis Purpura, Thrombotic Thrombocytopenic / complications*, diagnosis, therapy Sepsis / complications Status Epilepticus / diagnosis, etiology*, therapy Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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