| Prolonged pulseless perfusion in unanesthetized calves. | |
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MedLine Citation:
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PMID: 985069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nonpulsatile left ventricular (LV) bypass was achieved in nine alert, active calves for periods of up to two weeks using a centrifugal blood pump. Data were compared to prebypass control values and to results obtained from seven calves that underwent nonthoracotomy, retrograde LV cannulation, and pulsatile bypass for up to 35 days. Nonpulsatile flow produced an increase in heart rate of 20% (P less than .05) and an increase in aortic pressure of 10% (P less than .05). Cardiac output and systemic vascular resistance were similar in both groups for three days; thereafter, vascular resistance decreased as cardiac output progressively increased. Serum renin, lactate, and pyruvate values remained normal; creatinine clearances were not significantly different than control values, and there were no significant changes in body weight. These data indicate no untoward effects as a result of prolonged pulseless perfusion. |
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Authors:
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G G Johnston; F Hammill; U Marzec; D Gerard; K Johansen; R B Dilley; E F Bernstein |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of surgery (Chicago, Ill. : 1960) Volume: 111 ISSN: 0004-0010 ISO Abbreviation: Arch Surg Publication Date: 1976 Nov |
Date Detail:
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Created Date: 1976-12-23 Completed Date: 1976-12-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9716528 Medline TA: Arch Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1225-30 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia Animals Aorta / physiology Blood Pressure Blood Urea Nitrogen Body Weight Cardiac Output Cardiopulmonary Bypass / methods* Cattle Creatinine / blood Heart Rate Heart Ventricles Heart-Lung Machine Hemodynamics* Kidney / metabolism Lactates / blood Perfusion Pyruvates / blood Renin / blood Time Factors Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 0/Pyruvates; 60-27-5/Creatinine; EC 3.4.23.15/Renin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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