| Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent. | |
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MedLine Citation:
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PMID: 12746791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Treatment of neurocysticercosis with larvicidal agents is commonly complicated by seizures and transient neurologic deficits as a result of the host immune response to dying cysts. We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition. |
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Authors:
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Paul B Keiser; Theodore E Nash |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2003-05-09 |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 36 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-14 Completed Date: 2003-06-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: e122-6 Citation Subset: IM |
Affiliation:
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Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use* Albendazole / therapeutic use Animals Anthelmintics / therapeutic use* Edema / drug therapy Humans Male Methotrexate Middle Aged Neurocysticercosis / drug therapy*, immunology Praziquantel / therapeutic use* Taenia solium / drug effects, immunology* |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anthelmintics; 54965-21-8/Albendazole; 55268-74-1/Praziquantel; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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