| Prolonged paradoxical response to anti-tuberculous treatment after infliximab. | |
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MedLine Citation:
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PMID: 20579914 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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A 56-year-old woman with ankylosing spondylitis, treated for 3 months with infliximab, developed miliary tuberculosis with mediastinal lymphadenopathies and brain and splenic lesions. After initial improvement under anti-tuberculous therapy, she suffered an unexpectedly prolonged paradoxical worsening with several episodes of lymphadenopathy, including life-threatening ones, over a period of more than 14 months of follow-up. The outcome was favorable as a result of corticosteroid and surgical treatments. This phenomenon reflects a paradoxical reaction precipitated by infliximab withdrawal. |
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Authors:
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Sara Melboucy-Belkhir; Gabriella Flexor; Jérôme Stirnemann; Anne-Sophie Morin; Latifatou Boukari; Claude Polliand; Philippe Cruaud; Olivier Fain |
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Publication Detail:
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Type: Journal Article Date: 2010-06-25 |
Journal Detail:
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Title: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Volume: 14 Suppl 3 ISSN: 1878-3511 ISO Abbreviation: Int. J. Infect. Dis. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-10-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610933 Medline TA: Int J Infect Dis Country: Canada |
Other Details:
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Languages: eng Pagination: e333-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Service de Médecine Interne, Hôpital Jean-Verdier, Assistance Publique-Hôpitaux de Paris, Université Paris 13, avenue du 14 Juillet, Bondy Cedex, France. melboucysara@yahoo.fr |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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