| Prolonged lung retention of 131I-HIPDM in smokers. | |
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MedLine Citation:
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PMID: 7877826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-five subjects were divided into 4 groups; the first group was composed of 8 healthy nonsmoking subjects; the second group included 8 healthy smokers; the third group included 12 nonsmoking patients suffering from chronic obstructive pulmonary emphysema; the fourth group was composed of 7 smokers with chronic obstructive pulmonary emphysema. N,N,N'-trimethyl-N'2-Hydroxy-3-Methyl-5-iodobenzyl-1,3-propanediamine iodine-131(HIPDM) was rapidly injected into the antecubital vein. The influence of 131I-HIPDM by lung clearance was analysed thought imaging of lung and ratio of prolongation of 131I-HIPDM in the lung. Prolongation of 131I-HIPDM in the lung was shown in the smokers with chronic obstructive pulmonary emphysema in 60 minutes, and the healthy smokers, smokers with chronic obstructive pulmonary emphysema in the 24 hours after the injection of 131I-HIPDM. Smoking is an important factor of disturbance of lung clearance. |
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Authors:
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C T Liu; D L Wang; A Oliaro; N Q Huang; J H Tian |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Panminerva medica Volume: 36 ISSN: 0031-0808 ISO Abbreviation: Panminerva Med Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1995-04-04 Completed Date: 1995-04-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0421110 Medline TA: Panminerva Med Country: ITALY |
Other Details:
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Languages: eng Pagination: 128-30 Citation Subset: IM |
Affiliation:
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Department of Respiration, Chinese PLA General Hospital, Beijing. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chronic Disease Female Humans Iodine Radioisotopes / diagnostic use Iodobenzenes / pharmacokinetics* Male Metabolic Clearance Rate Middle Aged Pulmonary Emphysema / metabolism* Smoking / metabolism* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes; 0/Iodobenzenes; 84718-97-8/N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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