Document Detail


Prolonged intravenous eptifibatide infusion for prevention of coronary stent thrombosis.
MedLine Citation:
PMID:  16581146     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Coronary bare-metal stent thrombosis usually occurs within a week of angioplasty, and may result in myocardial infarction and death. Thrombosis is effectively prevented by antiplatelet therapy with aspirin and clopidogrel. We describe a patient who was unable to ingest oral medication after angioplasty due to gastrointestinal surgery, and was therefore at risk for stent thrombosis. Intravenous eptifibatide was infused for 8 days in order to achieve parenteral platelet inhibition. We suggest a role for long-term intravenous administration of glycoprotein IIb/IIIa inhibitors for prevention of stent thrombosis in patients unable to take oral antiplatelet therapy.
Authors:
Ronen Jaffe; David A Halon; Julia Carmeli; Judith Carmeli; Basil S Lewis
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Publication Detail:
Type:  Case Reports; Letter     Date:  2006-04-03
Journal Detail:
Title:  International journal of cardiology     Volume:  114     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-12     Completed Date:  2007-01-30     Revised Date:  2010-07-23    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  409-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Coronary Angiography
Coronary Stenosis / prevention & control*,  radiography
Graft Occlusion, Vascular / prevention & control*,  radiography
Humans
Male
Myocardial Infarction / therapy
Peptides / therapeutic use*
Platelet Aggregation Inhibitors / therapeutic use*
Stents*
Chemical
Reg. No./Substance:
0/Peptides; 0/Platelet Aggregation Inhibitors; 0/eptifibatide
Comments/Corrections
Erratum In:
Int J Cardiol. 2010 Jul 23;142(3):307
Note: Carmeli, Judith [corrected to Carmeli, Julia]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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