Document Detail

Prolonged intrahepatic cholestasis and renal failure secondary to anabolic androgenic steroid-enriched dietary supplements.
MedLine Citation:
PMID:  19238093     Owner:  NLM     Status:  MEDLINE    
The illegal enrichment of anabolic androgenic steroids in over-the-counter dietary supplements is well documented, but the health consequences have not been widely recognized. Three recent reports document cholestatic jaundice and nephropathy due to these compounds. We present 3 additional cases of anabolic androgenic steroid-enriched dietary supplement-induced hepatotoxicity and 1 case of renal failure, and we review the literature and the relevant features of this growing health concern. Recognition of this entity could obviate the need for invasive diagnostic testing and hospitalization and facilitate diagnosis and appropriate counseling.
Prashant V Krishnan; Zhen-Zhou Feng; Stuart C Gordon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  43     ISSN:  1539-2031     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-20     Completed Date:  2009-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-5     Citation Subset:  IM    
Division of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 48202, USA.
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MeSH Terms
Anabolic Agents / adverse effects*
Androgens / adverse effects
Cholestasis, Intrahepatic / chemically induced*
Dietary Supplements / adverse effects*
Kidney Failure / chemically induced*
Young Adult
Reg. No./Substance:
0/Anabolic Agents; 0/Androgens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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