| Prolonged fetal bradycardia as the presenting clinical sign in congenital syphilis complicated by necrotizing funisitis: a case report. | |
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MedLine Citation:
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PMID: 21766037 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Syphilis remains a serious cause of neonatal morbidity and mortality worldwide. In this paper, we describe a case of congenital syphilis that was fully supported by abnormal fetal heart rate patterns and placental histopathological evidence. A 24-year-old para 4 woman, who did not attend antenatal care, was admitted to our hospital with a complaint of abdominal discomfort at an estimated 31-week gestation. Fetal heart rate monitoring showed prolonged bradycardia. A neonate weighting 1,423 g with severe birth asphyxia was immediately delivered by cesarean section. Following delivery, the mother and the neonate were diagnosed with syphilis. Histopathological examination confirmed severe chorioamnionitis and necrotizing funisitis with numerous Treponema pallidum. Conclusions. Challenges in establishing the diagnosis of necrotizing funisitis are essential for optimal management of a fetus with a systemic inflammatory response in utero. |
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Authors:
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Jun Kakogawa; Miyuki Sadatsuki; Norio Masuya; Hideto Gomibuchi; Shigeki Minoura; Kazuhusa Hoshimoto |
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Publication Detail:
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Type: Journal Article Date: 2011-04-06 |
Journal Detail:
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Title: ISRN obstetrics and gynecology Volume: 2011 ISSN: 2090-4444 ISO Abbreviation: ISRN Obstet Gynecol Publication Date: 2011 |
Date Detail:
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Created Date: 2011-07-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101558763 Medline TA: ISRN Obstet Gynecol Country: Egypt |
Other Details:
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Languages: eng Pagination: 320246 Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynecology, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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