Document Detail

Prolonged fetal bradycardia as the presenting clinical sign in congenital syphilis complicated by necrotizing funisitis: a case report.
MedLine Citation:
PMID:  21766037     Owner:  NLM     Status:  In-Data-Review    
Syphilis remains a serious cause of neonatal morbidity and mortality worldwide. In this paper, we describe a case of congenital syphilis that was fully supported by abnormal fetal heart rate patterns and placental histopathological evidence. A 24-year-old para 4 woman, who did not attend antenatal care, was admitted to our hospital with a complaint of abdominal discomfort at an estimated 31-week gestation. Fetal heart rate monitoring showed prolonged bradycardia. A neonate weighting 1,423 g with severe birth asphyxia was immediately delivered by cesarean section. Following delivery, the mother and the neonate were diagnosed with syphilis. Histopathological examination confirmed severe chorioamnionitis and necrotizing funisitis with numerous Treponema pallidum. Conclusions. Challenges in establishing the diagnosis of necrotizing funisitis are essential for optimal management of a fetus with a systemic inflammatory response in utero.
Jun Kakogawa; Miyuki Sadatsuki; Norio Masuya; Hideto Gomibuchi; Shigeki Minoura; Kazuhusa Hoshimoto
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Publication Detail:
Type:  Journal Article     Date:  2011-04-06
Journal Detail:
Title:  ISRN obstetrics and gynecology     Volume:  2011     ISSN:  2090-4444     ISO Abbreviation:  ISRN Obstet Gynecol     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101558763     Medline TA:  ISRN Obstet Gynecol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  320246     Citation Subset:  -    
Department of Obstetrics and Gynecology, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
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