| Prolonged exposure to angiotensin-converting enzyme inhibitors during pregnancy. Fetal toxicity could be reversible. | |
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MedLine Citation:
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PMID: 16250418 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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QUESTION: I read in a Motherisk Update that angiotensin-converting enzyme (ACE) inhibitors are contraindicated during pregnancy. Many women, however, do not know they are pregnant for quite some time after conception. One of my patients was taking ACE inhibitors for 3 to 4 months while she was pregnant. How should I advise her? ANSWER: The deleterious effects ACE inhibitors have on fetuses were seen only after exposure during the second and third trimesters and were mostly secondary to renal damage. These effects can be reversed, as described in this Motherisk Update. |
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Authors:
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A Shrim; H Berger; J Kingdom; A Hamoudi; P S Shah; G Koren |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Canadian family physician Médecin de famille canadien Volume: 51 ISSN: 0008-350X ISO Abbreviation: Can Fam Physician Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-27 Completed Date: 2005-12-01 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0120300 Medline TA: Can Fam Physician Country: Canada |
Other Details:
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Languages: eng Pagination: 1335-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angiotensin-Converting Enzyme Inhibitors / adverse effects* Female Humans Infant, Newborn Oligohydramnios / chemically induced* Pregnancy Pregnancy Trimester, Second Prenatal Exposure Delayed Effects / prevention & control* Ramipril / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin-Converting Enzyme Inhibitors; 87333-19-5/Ramipril |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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