| Prolonged benefit in the treatment of chronic idiopathic urticaria with astemizole. | |
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MedLine Citation:
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PMID: 1976298 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A double-blind clinical trial of 51 patients with chronic idiopathic urticaria using oral astemizole for 8 weeks demonstrated significant improvement in symptoms and lesions in 75% of treated patients versus 20% in the placebo group. The suppression of urticaria persisted for an average of 38 days, demonstrating the long duration of action of astemizole. |
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Authors:
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R W Honsinger; R J Thomsen |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of allergy Volume: 65 ISSN: 0003-4738 ISO Abbreviation: Ann Allergy Publication Date: 1990 Sep |
Date Detail:
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Created Date: 1990-10-19 Completed Date: 1990-10-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372346 Medline TA: Ann Allergy Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 194-200 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of New Mexico School of Medicine. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Astemizole Benzimidazoles / adverse effects, therapeutic use* Chronic Disease Clinical Trials as Topic Double-Blind Method Histamine H1 Antagonists / therapeutic use Humans Time Factors Urticaria / drug therapy*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Benzimidazoles; 0/Histamine H1 Antagonists; 68844-77-9/Astemizole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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