Document Detail

Prolonged benefit in the treatment of chronic idiopathic urticaria with astemizole.
MedLine Citation:
PMID:  1976298     Owner:  NLM     Status:  MEDLINE    
A double-blind clinical trial of 51 patients with chronic idiopathic urticaria using oral astemizole for 8 weeks demonstrated significant improvement in symptoms and lesions in 75% of treated patients versus 20% in the placebo group. The suppression of urticaria persisted for an average of 38 days, demonstrating the long duration of action of astemizole.
R W Honsinger; R J Thomsen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of allergy     Volume:  65     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-10-19     Completed Date:  1990-10-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  194-200     Citation Subset:  IM    
Department of Medicine, University of New Mexico School of Medicine.
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MeSH Terms
Benzimidazoles / adverse effects,  therapeutic use*
Chronic Disease
Clinical Trials as Topic
Double-Blind Method
Histamine H1 Antagonists / therapeutic use
Time Factors
Urticaria / drug therapy*,  pathology
Reg. No./Substance:
0/Benzimidazoles; 0/Histamine H1 Antagonists; 68844-77-9/Astemizole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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