| Proliferative activity in endometrial hyperplasia and adenocarcinoma. | |
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MedLine Citation:
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PMID: 11374806 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies on the proliferative activity of cells in endometrial hyperplasia and adenocarcinoma were performed using techniques detecting Proliferating Cell Nuclear Antigen (PCNA) and Nucleolar Organizer Regions (NORs). PCNA expression was defined as the percentage of nuclei showing reactivity in 200 cells per sample. The mean AgNOR count per cell was calculated following the analysis of at least 100 nuclei per sample at a magnification of x 400. Student-t test was used for the statistical analysis. The results obtained indicate that the evaluation of cell proliferative activity expressed by AgNOR count and PCNA index can help in the distinction between atypical hyperplasia and well-differentiated adenocarcinoma, and thus can serve as a useful pathological criterion. |
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Authors:
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S Terlikowski; A Lenczewski; W Famulski; M Sulkowska; M Kulikowski |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society Volume: 39 ISSN: 0239-8508 ISO Abbreviation: Folia Histochem. Cytobiol. Publication Date: 2001 |
Date Detail:
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Created Date: 2001-05-25 Completed Date: 2001-10-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502651 Medline TA: Folia Histochem Cytobiol Country: Poland |
Other Details:
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Languages: eng Pagination: 163-4 Citation Subset: IM |
Affiliation:
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Department of Gynecology and Septic Obstetrics, Medical Academy, Białystok, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology* Antibodies, Monoclonal / diagnostic use Cell Division Endometrial Hyperplasia / pathology* Endometrial Neoplasms / pathology* Female Humans Nucleolus Organizer Region / pathology Proliferating Cell Nuclear Antigen / immunology Silver Staining |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Proliferating Cell Nuclear Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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