Document Detail


Proliferation and morphology of ascitic cells as a function of age in cell culture.
MedLine Citation:
PMID:  1054533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ascitic cells in the logarithmic growth phase increase the accumulation of glycogen particles in the course of explantation into suspension culture, probably due to the increasing arrest of glycogenolytic enzymes. At this age, a part of the cells are capable of restitution by exopinocytosis of the glycogen-containing vacuoles ia formation of cytoplasmic buds. Older cells, taken from the plateau-phase, pass atypical differentiation and ageing, are less capable of hindering the abnormal accumulation of glycogen and the hypervacuolisation. As a consequence, the cells finally degenerate and die.
Authors:
A Balázs; L Holczinger; I Fazekas; G Turi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  53     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  1975  
Date Detail:
Created Date:  1975-06-02     Completed Date:  1975-06-02     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  529-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Ascitic Fluid
Cell Biology*
Cell Differentiation
Cell Division*
Cell Line*
Cell Survival*
Glycogen / metabolism*
Leukemia, Myeloid, Acute*
Microscopy, Electron
Mitosis
Models, Biological
Rats
Chemical
Reg. No./Substance:
9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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