| Proliferation of cardiomyocytes: a question unresolved. | |
| | |
MedLine Citation:
|
PMID: 19482667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In the past, human heart has been considered a post-mitotic organ formed by cells, like adult cardiomyocytes, terminally differentiated and incapable of proliferation. This paradigm has been shaken by recent works indicating that postnatal adult cardiomyocytes are able to re-enter in the cell cycle and proliferate. In this view, the understanding of main candidates regulating cardiomyocyte cell cycle is of vital importance for future clinical approach. |
| | |
Authors:
|
Maria De Falco; Gilda Cobellis; Antonio De Luca |
Related Documents
:
|
8674727 - E2f and the molecular mechanisms of early cell-cycle control. 17237107 - Merging microarray cell synchronization experiments through curve alignment. 15118337 - Effect of ethanol on cell growth of budding yeast: genes that are important for cell gr... 17172867 - Human cdc14a reverses cdk1 phosphorylation of cdc25a on serines 115 and 320. 3184207 - Ganglioside gm1 actions on cell-substratum adhesion and dna synthesis by cultured astro... 15264307 - Osteoblast-like cell response to bioactive composites-surface-topography and compositio... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2009-06-01 |
Journal Detail:
|
Title: Frontiers in bioscience (Elite edition) Volume: 1 ISSN: 1945-0508 ISO Abbreviation: Front Biosci (Elite Ed) Publication Date: 2009 |
Date Detail:
|
Created Date: 2009-06-01 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101485240 Medline TA: Front Biosci (Elite Ed) Country: United States |
Other Details:
|
Languages: eng Pagination: 528-36 Citation Subset: IM |
Affiliation:
|
Department of Biological Sciences, Section of Evolutionary and Comparative Biology, University Federico II of Naples, Naples, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cell Cycle / physiology* Cell Proliferation* Gene Expression Regulation, Developmental / physiology* Heart / growth & development* Humans Mitogen-Activated Protein Kinases / metabolism Myocytes, Cardiac / cytology*, physiology* Signal Transduction / physiology* |
| Chemical | |
Reg. No./Substance:
|
EC 2.7.11.24/Mitogen-Activated Protein Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiac conduction disorders in children.
Next Document: Cerebellar haemorrhages and pons development in extremely low birth weight infants.