Document Detail


Prolapsing mucosal polyps: an underrecognized form of colonic polyp--a clinicopathological study of 15 cases.
MedLine Citation:
PMID:  11866275     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Prolapsing intestinal mucosa occurs in many forms throughout the GI tract. We describe 15 patients with polypoid masses in the sigmoid colon and histological features of mucosal prolapse. METHODS: Fifteen patients with colon polyps demonstrating endoscopic and histological features of mucosal prolapse were retrospectively identified from our database. RESULTS: Twelve patients presented with signs and symptoms that were nonspecific, but consistent with mucosal prolapse, such as occult or gross intestinal bleeding and lower abdominal pain. Three patients were asymptomatic. The polyps occurred in the sigmoid colon, usually in association with diverticular disease, and appeared more often in men. Endoscopically, the polyps appeared to be well-circumscribed, hyperemic masses that contrasted sharply with normal-appearing adjacent mucosa. Histological features include glandular crypt abnormalities, fibromuscular obliteration of the lamina propria, and thickened and splayed muscularis mucosa. CONCLUSIONS: Prolapsing mucosal polyps of the colon are histologically similar to other mucosal prolapsing conditions in the GI tract, such as the solitary rectal ulcer syndrome, inflammatory cloacogenic polyps, inflammatory "cap" polyps, and gastric antral vascular ectasia, and should therefore be designated as part of the "mucosal prolapse syndrome."
Authors:
D A Tendler; S Aboudola; J F Zacks; M J O'Brien; C P Kelly
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  97     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-27     Completed Date:  2002-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  370-6     Citation Subset:  IM    
Affiliation:
Division of Gastroenterogy, Duke University Medical Center, Durham, North Carolina 7710, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Biopsy, Needle
Colonic Polyps / pathology*
Female
Humans
Immunohistochemistry
Intestinal Mucosa / pathology
Male
Middle Aged
Prolapse
Retrospective Studies
Sensitivity and Specificity
Sigmoid Neoplasms / pathology*
Sigmoidoscopy / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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