Document Detail

Prolapsed valve of the foramen ovale in newborns and infants with coarctation of the aorta.
MedLine Citation:
PMID:  3347588     Owner:  NLM     Status:  MEDLINE    
Out of 60 newborns and infants with symptomatic coarctation of the aorta, 34 had a significant left-to-right shunt at atrial level. In 20 of these 34 children, the atrial shunt had disappeared after surgical correction of the coarctation. All patients with this "reversible" shunt, thought to be secondary to an incompetent valve of the foramen ovale, were younger than 35 days at first cardiac catheterization. Left atrial pressure and left atrial volume of these patients did not differ significantly from those in a control group without atrial shunt. The conditions necessary for the development of a valve-incompetent foramen ovale include not only an increased left ventricular work load, but also a thin and pliable valve of the foramen ovale. It is only in infants younger than one month of age that the valve is thin and pliable enough to prolapse through the foramen ovale and form a channel between the two atria, which results in a left-to-right atrial shunt.
E Jentsch; R Liersch; M Bourgeois
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  9     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:  1988  
Date Detail:
Created Date:  1988-04-11     Completed Date:  1988-04-11     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-32     Citation Subset:  IM    
Department of Pediatric Cardiology, University of Düsseldorf, FRG.
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MeSH Terms
Aortic Coarctation / pathology*,  physiopathology,  surgery
Child, Preschool
Heart Catheterization
Heart Septal Defects, Atrial / pathology*,  physiopathology
Heart Septum / pathology*,  physiopathology
Heart Ventricles / physiopathology
Infant, Newborn
Retrospective Studies

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