Document Detail


Prolapse gastropathy syndrome may be a predictor of pathologic acid reflux.
MedLine Citation:
PMID:  18810781     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To assess the occurrence of gastric acid reflux into the esophagus in endoscopically confirmed prolapse gastropathy syndrome (PGS).
METHODS: Using ambulatory esophageal pH measurement (BRAVO(TM) wireless esophageal pH monitoring system), twenty-six patients with PGS were compared with twenty-one patients with erosive esophagitis (EE) as controls. We assessed several reflux parameters, including the percentage of total time at pH < 4, and the DeMeester score.
RESULTS: There were no statistical differences between the PGS group and the EE group as to mean age, sex ratio and pH recording time. The EE group showed more severe reflux than the PGS group, as evaluated in terms of the longest duration of reflux, the number of reflux episodes, the number of reflux episodes lasting > 5 min, the total time with pH < 4 during acid reflux episodes, and the DeMeester score, but none of these parameters showed statistically significant difference. Although 53.8% (14/26) of the PGS group and 76.2% (16/21) of the EE group demonstrated pathologic acid reflux (DeMeester score > 14.72), there was no statistically significant difference between the two groups in the incidence of pathologic acid reflux (P = 0.11).
CONCLUSION: There was no statistically significant difference in pathologic acid reflux between the PGS and EE group. These data suggest that endoscopically diagnosed PGS might be a predictor of pathologic acid reflux.
Authors:
Jin-Soo Kim; Hyung-Keun Kim; Young-Seok Cho; Hiun-Suk Chae; Byung-Wook Kim; Jin-Il Kim; Sok-Won Han; Kyu-Yong Choi
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  14     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-23     Completed Date:  2008-12-11     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  5601-5; discussion 5604     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Uijeongbu St. Mary's Hospital, 65-1 Geumo-dong, Uijeongbu city, Kyunggido, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Esophageal pH Monitoring
Esophagitis / complications*,  pathology
Esophagoscopy
Female
Gastroesophageal Reflux / etiology*,  pathology
Gastroscopy
Humans
Male
Middle Aged
Prolapse
Prospective Studies
Risk Factors
Severity of Illness Index
Stomach Diseases / complications*,  pathology
Syndrome
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