| Prolactin, hyperprolactinaemia and antipsychotic treatment: a review and lessons for treatment of early psychosis. | |
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MedLine Citation:
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PMID: 22472310 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Hyperprolactinaemia is a common side effect of antipsychotics; markedly raised levels are less common. Higher levels of prolactin result from longer exposure to higher doses, especially with older antipsychotics or with risperidone, sulpiride or amisulpride. Galactorrhoea, gynaecomastia, menstrual abnormalities and sexual dysfunction including hypogonadism and fertility problems are consequences of raised prolactin, and in the longer-term bone demineralisation. Younger patients may be more susceptible to hyperprolactinaemia. Trial reports often fail to state the frequency of raised levels. |
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Authors:
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John Cookson; Richard Hodgson; Hiram J Wildgust |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-2 |
Journal Detail:
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Title: Journal of psychopharmacology (Oxford, England) Volume: - ISSN: 1461-7285 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8907828 Medline TA: J Psychopharmacol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Burdett House, Mile End Hospital, London, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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