Document Detail

Project Pró-natal: population-based study of perinatal and infant mortality in natal, Northeast Brazil.
MedLine Citation:
PMID:  10594129     Owner:  NLM     Status:  MEDLINE    
The Pró-Natal project is a collaborative initiative that aims to improve maternal and infant health in a deprived community in Natal, Northeast Brazil. To assess the perinatal and infant mortality in this population of 40,000, we have collected over a 2-year period a consecutive series of 39 autopsy examinations on deaths under 1 year of age. During this period there were 2212 live births in the study population. The 14 perinatal deaths are described using the Wrigglesworth classification, and the 25 infant deaths, using a clinicopathological system. The contribution of normally formed stillbirths was small (14%), which probably reflects the underreporting of stillbirths in this community. The most common cause of death in the live births was complications of prematurity (43%). Specific causes (22%) of perinatal deaths were predominantly infections, including one case of congenital syphilis. Perinatal asphyxia was diagnosed in 14%, and there was one case (7%) of a chromosome abnormality. Infant deaths were predominantly due to respiratory (45%) and gastrointestinal infections (28%), with chronic malnutrition as an underlying cause in 80% of cases. Prenatal care could theoretically have prevented three of the perinatal deaths, and a further six deaths could have been avoided by improved management of labor and the immediate neonatal period. Prevention of malnutrition and improved treatment of acute infections would contribute to a reduction in infant mortality in this population. The Pró-Natal project will use these data to design preventative interventions to reduce perinatal and infant mortality in this community.
A M Ramos; T D Maranhão; A S Macedo; J I Pollock; A M Emond
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  3     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2000 Jan-Feb
Date Detail:
Created Date:  2000-01-18     Completed Date:  2000-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-35     Citation Subset:  IM    
Universidade Federal do Rio Grande do Norte, Center for Health Sciences, Departments of Pathology and Obstetrics, Av Nilo Peçanha 259, Petrópolis, 59012-300 Natal RN, Brazil.
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MeSH Terms
Gestational Age
Infant Mortality*
Infant, Newborn

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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