Document Detail


Project-focused activity and knowledge tracker: a unified data analysis, collaboration, and workflow tool for medicinal chemistry project teams.
MedLine Citation:
PMID:  19899777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Advances in the field of drug discovery have brought an explosion in the quantity of data available to medicinal chemists and other project team members. New strategies and systems are needed to help these scientists to efficiently gather, organize, analyze, annotate, and share data about potential new drug molecules of interest to their project teams. Herein we describe a suite of integrated services and end-user applications that facilitate these activities throughout the medicinal chemistry design cycle. The Automated Data Presentation (ADP) and Virtual Compound Profiler (VCP) processes automate the gathering, organization, and storage of real and virtual molecules, respectively, and associated data. The Project-Focused Activity and Knowledge Tracker (PFAKT) provides a unified data analysis and collaboration environment, enhancing decision-making, improving team communication, and increasing efficiency.
Authors:
Marian D Brodney; Arthur D Brosius; Tracy Gregory; Steven D Heck; Jacquelyn L Klug-McLeod; Christopher S Poss
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of chemical information and modeling     Volume:  49     ISSN:  1549-960X     ISO Abbreviation:  J Chem Inf Model     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-28     Completed Date:  2010-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230060     Medline TA:  J Chem Inf Model     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2639-49     Citation Subset:  IM    
Affiliation:
Data and Design Analytics, Computational Sciences Center of Emphasis, and Neuroscience Chemistry, Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340.
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MeSH Terms
Descriptor/Qualifier:
Chemistry, Pharmaceutical / methods*,  organization & administration
Communication
Cooperative Behavior*
Drug Design
Group Processes*
Industry
Information Storage and Retrieval
Knowledge
Statistics as Topic / methods*
User-Computer Interface
Workflow*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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