Document Detail

Progressive resistance exercise improves glycaemic control in people with type 2 diabetes mellitus: a systematic review.
MedLine Citation:
PMID:  19929766     Owner:  NLM     Status:  MEDLINE    
QUESTION: Is progressive resistance exercise a safe and effective form of exercise to improve glycaemic control in people with type 2 diabetes?
DESIGN: Systematic review with meta-analysis of randomised controlled trials.
PARTICIPANTS: People with type 2 diabetes mellitus.
INTERVENTION: Progressive resistance exercise.
OUTCOME MEASURES: The primary outcome was glycaemic control measured as percentage glycosylated haemoglobin (HbA1c). Secondary outcomes were body composition (lean body and fat free mass in kg), and muscle strength (% change in 1RM, dynamometry, change in maximum weight lifted).
RESULTS: The search yielded nine relevant trials that evaluated 372 people with type 2 diabetes. Compared to not exercising, progressive resistance exercise led to small and statistically significant absolute reductions in HbA1c of 0.3% (SMD -0.25, 95% CI -0.47 to -0.03). When compared to aerobic exercise there were no significant differences in HbA1c. Progressive resistance exercise resulted in large improvements in strength when compared to aerobic (SMD 1.44, 95% CI 0.83 to 2.05) or no exercise (SMD 0.95, 95% CI 0.58 to 1.31). There were no significant changes in body composition.
CONCLUSIONS: Progressive resistance exercise increases strength and leads to small reductions in glycosylated haemoglobin that are likely to be clinically significant for people with type 2 diabetes. Progressive resistance exercise is a feasible option in the management of glycaemia for this population.
Casey Irvine; Nicholas F Taylor
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Review    
Journal Detail:
Title:  The Australian journal of physiotherapy     Volume:  55     ISSN:  0004-9514     ISO Abbreviation:  Aust J Physiother     Publication Date:  2009  
Date Detail:
Created Date:  2009-11-25     Completed Date:  2010-02-19     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  0370615     Medline TA:  Aust J Physiother     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  237-46     Citation Subset:  IM    
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MeSH Terms
Blood Glucose / metabolism*
Body Composition / physiology
Diabetes Mellitus, Type 2 / blood,  physiopathology,  therapy*
Hemoglobin A, Glycosylated / metabolism
Outcome Assessment (Health Care)
Resistance Training / methods*
Reg. No./Substance:
0/Blood Glucose; 0/Hemoglobin A, Glycosylated

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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