Document Detail


Progressive outer retinal necrosis in a patient with nephrotic syndrome.
MedLine Citation:
PMID:  11195746     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Progressive outer retinal necrosis syndrome (PORN) is a variant of necrotizing herpetic retinopathy and the majority of the described cases were related to acquired immunodeficiency syndrome. We present a patient who is HIV negative with nephrotic syndrome and prednisolone use for 4 months who showed clinical features of PORN. Low CD4 counts and lymphocytopenia suggested immunosuppression. In the left eye, tractional retinal detachment at the posterior pole followed by incomplete posterior vitreous detachment developed. In addition to intravenous administration of acyclovir, vitreous surgeries including stripping of the posterior hyaloid and silicone-oil tamponade were successfully performed to repair the retinal detachment in the left eye and to prevent it in the right eye.
Authors:
K Shinoda; M Inoue; S Ishida; S Kawashima; T Wakabayashi; S Suzuki; H Katsura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmic surgery and lasers     Volume:  32     ISSN:  1082-3069     ISO Abbreviation:  Ophthalmic Surg Lasers     Publication Date:    2001 Jan-Feb
Date Detail:
Created Date:  2001-01-19     Completed Date:  2001-03-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9517132     Medline TA:  Ophthalmic Surg Lasers     Country:  United States    
Other Details:
Languages:  eng     Pagination:  67-72     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
CD4 Lymphocyte Count
Female
Fluorescein Angiography
Fundus Oculi
Glucocorticoids / therapeutic use
HIV Seronegativity
Humans
Lymphopenia / complications
Nephrotic Syndrome / complications*,  drug therapy
Prednisolone / therapeutic use
Retinal Detachment / etiology,  surgery
Retinal Necrosis Syndrome, Acute / complications*,  pathology
Visual Fields
Vitrectomy
Vitreous Detachment / etiology,  surgery
Chemical
Reg. No./Substance:
0/Glucocorticoids; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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