| Progressive necrotic myelopathy as a paraneoplastic syndrome: report of a case and some pathogenetic considerations. | |
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MedLine Citation:
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PMID: 1732404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Progressive necrotic myelopathy is a syndrome characterized by a spotty necrotic degeneration of the whole spinal cord in both anterior and posterior horns. This syndrome was recorded in a man suffering from a lymphoplasmatocytoid lymphoma. Whilst the usual evolution of this neurological syndrome is inexorably fatal, our case had a better outcome, due to the good response of the neoplasm to therapy. Progressive necrotic myelopathy is an uncommon complication of cancer, but it is probably incorrectly recognized in a number of cases. Two possible pathogenetic hypotheses are suggested: an autoimmune or an infective mechanism. |
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Authors:
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G Grignani; P G Gobbi; G Piccolo; D Bertoloni; A Rossi; C Pieresca; M C Legnani; E Ascari |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of internal medicine Volume: 231 ISSN: 0954-6820 ISO Abbreviation: J. Intern. Med. Publication Date: 1992 Jan |
Date Detail:
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Created Date: 1992-02-27 Completed Date: 1992-02-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8904841 Medline TA: J Intern Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 81-5 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, I.R.C.C.S. Policlinico S. Matteo, Pavia, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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complications Humans Male Middle Aged Necrosis Paraneoplastic Syndromes / complications*, immunology Spinal Cord Diseases / etiology, immunology, pathology* |
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