Document Detail


Progressive multifocal leukoencephalopathy and palliative care: A report of three cases and review of the literature.
MedLine Citation:
PMID:  22740610     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Progressive multifocal leukoencephalopathy (PML) is a rare but usually fatal demyelinating disease of the central nervous system in patients who are immunocompromised. It is characterized by rapid neurological deterioration associated with progressive white matter changes on imaging and is confirmed by isolation of the causative virus in the cerebrospinal fluid or brain tissue. Currently there are no effective treatments for PML and outcomes remain poor even after reversal of the immunocompromised state. This case series describes three patients with different underlying pathologies and varying presentations who were all diagnosed with PML and referred to a palliative care service.
Authors:
Penelope Janet Helen Cotton; Brian Le
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-27
Journal Detail:
Title:  Palliative medicine     Volume:  -     ISSN:  1477-030X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8704926     Medline TA:  Palliat Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Royal Melbourne Hospital, Department of Palliative Care, Australia.
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