Document Detail

Progressive familial heart block type II (PFHBII): a clinical profile from 1977 to 2003.
MedLine Citation:
PMID:  15258623     Owner:  NLM     Status:  MEDLINE    
An evaluation of a 38-year-old Caucasian woman, who was referred to Tygerberg Hospital (Western Cape Province, RSA) with Wenckebach second-degree or possibly complete atrioventricular (AV) block that had progressed from first-degree AV block, identified a family history of the cardiac conduction system disorder progressive familial heart block type II (PFHBII). This prompted a retrospective clinical review of the subjects described in the original study, as well as additional family members who had not been examined in the original study. Progression of clinical features was observed, but more importantly, PFHBII was clinically redefined as an AV nodal disorder, which may progress to dilated cardiomyopathy (DCM).
P Fernandez; V A Corfield; P A Brink
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners     Volume:  15     ISSN:  -     ISO Abbreviation:  Cardiovasc J S Afr     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-07-19     Completed Date:  2004-12-22     Revised Date:  2014-01-13    
Medline Journal Info:
Nlm Unique ID:  100964061     Medline TA:  Cardiovasc J S Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  129-32     Citation Subset:  IM    
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MeSH Terms
Disease Progression
Heart Block / epidemiology,  genetics*
Heart Conduction System / physiopathology*
Retrospective Studies
South Africa / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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