Document Detail


Progressive dystonia and paraparesis in cerebral palsy.
MedLine Citation:
PMID:  3948889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cerebral palsy (CP) was commonly considered as a static encephalopathy with various clinical forms. Among them the dystonic form may occur alone (15%) or combined with other manifestations (e.g. spasticity). In a country-wide survey of dystonia in Israel, we discovered 7 cases in whom dystonia and/or spastic paraparesis appeared or worsened on the background of CP. The clinical deterioration occurred between 14 and 40 years of age and resulted in a bedridden state in 2 of the 7 patients. The occurrence of extrapyramidal features and/or progressive spastic paraparesis in patients with preexisting CP was not clearly recognized in the literature, although lately some reports suggested 'changing motor patterns' in patients with CP. It is hypothesized that in some cases the pathological substrate, occurring at the perinatal period, may slowly progress in adult life. The fact that the majority of the dystonic subjects were Ashkenazi Jews is reminiscent of the high gene frequency of idiopathic torsion dystonia in this group, and suggests that the genetic tendency may be triggered off by perinatal factors.
Authors:
T Treves; A D Korczyn
Related Documents :
6359989 - Effects of inhaled budesonide alone and in combination with low-dose terbutaline in chi...
24092889 - A review of the specificity of exercises designed for conditioning the lumbar extensors.
3689629 - Inhibition of exercise-induced asthma by nifedipine: a dose-response study.
589779 - Ige, parasites and asthma in tanzanian children.
6752079 - Pharmacology of nomifensine.
3947039 - Contingent negative variation in headache.
21835619 - A single 30min treadmill exercise session is suitable for 'proof-of concept studies' in...
2718209 - Mitochondrial function after asphyxia in newborn lambs.
3415759 - An experimental test of risk compensation: between-subject versus within-subject analyses.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European neurology     Volume:  25     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1986  
Date Detail:
Created Date:  1986-04-24     Completed Date:  1986-04-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  148-53     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cerebral Palsy / complications*,  epidemiology
Dystonia / complications*,  epidemiology
Female
Humans
Israel
Jews
Male
Paraplegia / complications*,  epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dementia after stroke.
Next Document:  Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome.