| Progressive dystonia and paraparesis in cerebral palsy. | |
| | |
MedLine Citation:
|
PMID: 3948889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cerebral palsy (CP) was commonly considered as a static encephalopathy with various clinical forms. Among them the dystonic form may occur alone (15%) or combined with other manifestations (e.g. spasticity). In a country-wide survey of dystonia in Israel, we discovered 7 cases in whom dystonia and/or spastic paraparesis appeared or worsened on the background of CP. The clinical deterioration occurred between 14 and 40 years of age and resulted in a bedridden state in 2 of the 7 patients. The occurrence of extrapyramidal features and/or progressive spastic paraparesis in patients with preexisting CP was not clearly recognized in the literature, although lately some reports suggested 'changing motor patterns' in patients with CP. It is hypothesized that in some cases the pathological substrate, occurring at the perinatal period, may slowly progress in adult life. The fact that the majority of the dystonic subjects were Ashkenazi Jews is reminiscent of the high gene frequency of idiopathic torsion dystonia in this group, and suggests that the genetic tendency may be triggered off by perinatal factors. |
| | |
Authors:
|
T Treves; A D Korczyn |
Related Documents
:
|
23375799 - Functional autonomy, bone mineral density (bmd) and serum osteocalcin levels in older f... 21076349 - Management of exercise-induced bronchospasm in adolescents with asthma. 15700549 - A guinea pig model for cough variant asthma and role of tachykinins. 1617389 - Precipitating factors of asthma. 2943049 - Platelet activation during exercise induced asthma: effect of prophylaxis with cromogly... 8538549 - The chocuhaler: sweet deliverance in asthma management. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: European neurology Volume: 25 ISSN: 0014-3022 ISO Abbreviation: Eur. Neurol. Publication Date: 1986 |
Date Detail:
|
Created Date: 1986-04-24 Completed Date: 1986-04-24 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 148-53 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Cerebral Palsy / complications*, epidemiology Dystonia / complications*, epidemiology Female Humans Israel Jews Male Paraplegia / complications*, epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dementia after stroke.
Next Document: Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome.