Document Detail

Progressive cribriform and zosteriform hyperpigmentation: a clinicopathologic study.
MedLine Citation:
PMID:  22435426     Owner:  NLM     Status:  In-Data-Review    
Background  Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a disorder of pigmentation. Although several cases of PCZH have been reported, no clinicopathologic studies of the condition have been published in the English-language literature. Objectives  The purpose of this study was to determine the clinical characteristics and histologic findings of PCZH. Methods  Between 1999 and 2009, 30 patients were diagnosed with PCZH in our Department of Dermatology. Medical records, clinical photographs, and pathologic findings for each patient were retrospectively reviewed. Results  The patients included 16 men and 14 women. The mean age at onset was 14.27 years. The trunk was the most common site of involvement. Microscopic examination showed an increased level of melanin pigment in the basal cell layer compared with adjacent normal skin, although no significant difference existed in the number of melanocytes. Pigmentary incontinence was observed in 13 of 30 cases. Conclusions  There was no significant difference in prevalence, age at onset, and duration of lesions between male and female patients with PCZH. The lesions corresponded to the lines of Blaschko and were localized rather than exhibiting diffuse patterns. A common feature of the histopathologic findings was higher melanin content in the lesions than in normal skin but with no significant difference in the number of melanocytes.
Eujin Cho; Sang Hyun Cho; Jeong Deuk Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  51     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  399-405     Citation Subset:  IM    
Copyright Information:
© 2012 The International Society of Dermatology.
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
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