Document Detail


Progressive confluent circumpapillary multiple evanescent white-dot syndrome.
MedLine Citation:
PMID:  10511044     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe a morphologic variant of the multiple evanescent white-dot syndrome that can mimic other conditions. METHODS: We examined three patients with severe cases of unilateral multiple evanescent white-dot syndrome characterized by an atypical progressive circumpapillary discoloration of the fundus. RESULTS: The confluent circumpapillary lesion progressed toward or beyond the equator of the fundus, raising initial concern of a viral retinitis. However, pinpoint dots at the leading edge evolved into the typical wreath-like spots of multiple evanescent white-dot syndrome, which then coalesced into the advancing edge of a geographic retinitis or retinal pigment epitheliitis, before spontaneous resolution. CONCLUSION: Progressive geographic circumpapillary discoloration, appearing as a giant white spot, occurs rarely in severe cases of multiple evanescent white-dot syndrome. The distinctive appearance may suggest a disorder other than multiple evanescent white-dot syndrome, which can make initial diagnosis more difficult and lead to unnecessary or inappropriate testing and treatment.
Authors:
J K Luttrull; M F Marmor; M Nanda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  128     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-08     Completed Date:  1999-10-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  378-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Ophthalmology, School of Medicine, Stanford University, Stanford, California, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Disease Progression
Female
Fluorescein Angiography
Fundus Oculi
Humans
Male
Optic Disk / pathology*
Retinal Diseases / diagnosis*
Syndrome
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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