Document Detail

Progressive IgA nephropathy: the role of hypertension.
MedLine Citation:
PMID:  3140079     Owner:  NLM     Status:  MEDLINE    
A retrospective study of 67 patients with IgA nephropathy carried out at the Glasgow Royal Infirmary revealed an overall 10-year actuarial renal survival of 77.4%. At the time of presentation, 27 patients (40.3%) were hypertensive and 40 (59.7%) were normotensive. As expected, the survival was worse in the hypertensive group. However, when the effect of control of blood pressure was assessed, a significantly worse survival was found in those whose hypertension was inadequately controlled, compared to those whose hypertension was well controlled, in whom survival was not significantly different from that of the normotensive group. The differences in survival could not be explained by increased patient age nor by longer duration of disease. Good control of hypertension may prevent progression to end-stage renal failure in IgA nephropathy.
C D Payton; A McLay; J M Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  3     ISSN:  0931-0509     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  1988  
Date Detail:
Created Date:  1988-11-10     Completed Date:  1988-11-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  138-42     Citation Subset:  IM    
Renal Unit, Royal Infirmary, Glasgow, UK.
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MeSH Terms
Actuarial Analysis
Antihypertensive Agents / therapeutic use
Glomerulonephritis, IGA / complications,  mortality,  physiopathology*
Hypertension / drug therapy,  mortality,  physiopathology*
Kidney Failure, Chronic / etiology,  mortality,  prevention & control
Middle Aged
Retrospective Studies
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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