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Progressive Growth in Epibulbar Complex Choristomas: Report of 2 Cases and Review of Literature.
MedLine Citation:
PMID:  21885965     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE:: To report 2 patients with progressive complex choristomas and to review the literature on this subject. DESIGN:: Interventional case reports. METHODS:: Clinical and pathologic correlation was performed on 2 patients with progressive epibulbar choristomas. PubMed database was searched to identify all the previously reported cases of progressive epibulbar choristomas (using key words choristoma, dermoid, growth, progression, and evolution). RESULTS:: Growth of the epibulbar choristomas was noted in infancy in 1 patient with oculoectodermal syndrome and in puberty in another otherwise healthy patient. Both lesions were identified histopathologically as complex choristomas. In addition to the characteristic choristomatous tissues, both lesions demonstrated increased vascularity, inflammatory infiltrate, and fibroblast proliferation within myxomatous stroma. Review of the literature identified 4 patients with progressive complex choristomas, 1 of whom demonstrated histopathologic findings similar to those of the 2 cases reported here. CONCLUSIONS:: Epibulbar choristomas rarely enlarge, likely secondary to reactive changes within the tissue manifested by increased vascularity, inflammatory cell infiltration, and fibroblast proliferation with deposition of myxomatous stroma.
Authors:
Valerie Trubnik; Ryan Conley; David C Ritterband; Ira Udell; Glenn Thompson; Carolyn Shih; Steven A McCormick; Tatyana Milman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-31
Journal Detail:
Title:  Cornea     Volume:  -     ISSN:  1536-4798     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-9-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the *Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, NY and New York Medical College, Valhalla, NY; †Department of Ophthalmology, North Shore Long Island Jewish Health System, New Hyde Park, NY and Hofstra University, Hempstead, NY; and ‡Pathology and Laboratory Medicine, The New York Eye and Ear Infirmary, New York, NY.
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