| Progressive Epidural Lipomatosis with Steroid use in Severe Refractory Asthma. | |
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MedLine Citation:
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PMID: 21341972 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background. Long-term immunosuppression with oral corticosteroids is frequently used to treat inflammatory diseases of the lung and is advocated in the management of some patients with asthma. Methods. The authors describe the case of a 35-year-old man with severe refractory asthma who developed a slowly progressive thoracic spinal cord syndrome. Results. Spinal imaging demonstrated the presence of spinal epidural lipomatosis, a rare complication of prolonged corticosteroid therapy, which is characterized by overgrowth of fat in the epidural space and neuronal compression. Conclusions. Spinal epidural lipomatosis should be considered in patients receiving long-term corticosteroid therapy who develop symptoms and signs suggestive of spinal cord compression. |
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Authors:
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Benjamin Wakerley; Louisa Kent; Matthew Jackson |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-22 |
Journal Detail:
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Title: The Journal of asthma : official journal of the Association for the Care of Asthma Volume: - ISSN: 1532-4303 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106454 Medline TA: J Asthma Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Neurology, John Radcliffe Hospital, Oxford, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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