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Progression of paralysis is the most useful factor for differentiating malignant from benign intramedullary tumors.
MedLine Citation:
PMID:  23208538     Owner:  NLM     Status:  Publisher    
Study design:Retrospective study.Objectives:The purpose of this study was to identify the clinical factors for differentiating malignant from benign intramedullary spinal cord tumors.Setting:Niigata, Japan.Methods:We conducted a retrospective review of charts and images. Preoperative paralysis including walking ability, urinary function, magnetic resonance imaging (MRI) findings and pathological diagnosis were evaluated in 33 consecutive cases of intramedullary spinal cord tumor, and the clinical factors that were useful for differentiating malignant from benign tumors were identified.Results:Early progression of paralysis was the most valuable feature for differentiating malignant from benign tumors. Malignant tumors were suspected in only three of ten cases on the basis of MRI findings.Conclusion:Simple assessment of walking ability is easy to perform and is useful for predicting the pathological malignancy of intramedullary tumors of the spinal cord.Spinal Cord advance online publication, 4 December 2012; doi:10.1038/sc.2012.152.
T Ito; K Sawakami; S Ishikawa; T Hirano; N Endo; A Kakita; H Takahashi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-04
Journal Detail:
Title:  Spinal cord     Volume:  -     ISSN:  1476-5624     ISO Abbreviation:  Spinal Cord     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609749     Medline TA:  Spinal Cord     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Orthopaedic Surgery, Niigata City General Hospital, Niigata, Japan.
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