| Progression in primary angle closure eyes. | |
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MedLine Citation:
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PMID: 20164791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To study the long-term course of primary angle closure (PAC) eyes after iridotomy. METHODS: Seventy-two eyes of 72 patients diagnosed as PAC, having occludable angles with evidence of closure, but no ocular hypertension, were studied. Laser iridotomy was carried out in all eyes at baseline. Standard achromatic perimetry and tonometry were recorded at baseline and serially every 6 months, for at least 4 years. Changes on perimetry and the intraocular pressure (IOP) were analyzed. RESULTS: At 1 year, 10 eyes and at final review, 26 eyes had developed ocular hypertension and required topical antiglaucoma medication. Eight eyes developed visual field defects on standard achromatic perimetry, over a mean period of 6.89±2.4 years. Eyes that progressed on perimetry, had a significantly narrower angle recess, less than or equal to 10 degrees, P=0.04, and a higher baseline MD and PSD, P=0.004 and 0.03, respectively. They also showed having a larger intervisit IOP fluctuation of 8.9±2.3 mm Hg, cf stable eyes, 6.2±3 mm Hg, P=0.003, and a longer duration of follow-up, P=0.01. CONCLUSION: A third of PAC eyes, with very narrow angles, higher global indices, intervisit IOP fluctuations, and a longer duration of follow-up were observed to develop ocular hypertension. A third of the PAC eyes with hypertension, that is 11.1% overall, went on to develop PAC glaucoma. |
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Authors:
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Ramanjit Sihota; Aparna Rao; Viney Gupta; Geetha Srinivasan; Ajay Sharma |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of glaucoma Volume: 19 ISSN: 1536-481X ISO Abbreviation: J. Glaucoma Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-03 Completed Date: 2011-02-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9300903 Medline TA: J Glaucoma Country: United States |
Other Details:
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Languages: eng Pagination: 632-6 Citation Subset: IM |
Affiliation:
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Glaucoma Research Facility & Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. rjsihota@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Disease Progression Female Follow-Up Studies Glaucoma, Angle-Closure / physiopathology*, surgery Gonioscopy Humans Intraocular Pressure / physiology Iridectomy* Iris / surgery* Lasers, Solid-State / therapeutic use Male Middle Aged Ocular Hypertension / drug therapy, etiology, physiopathology Prospective Studies Tonometry, Ocular Visual Acuity / physiology Visual Field Tests Visual Fields / physiology |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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