| Progression of atherosclerosis after venous coronary artery bypass graft surgery: a 15-year follow-up study. | |
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MedLine Citation:
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PMID: 9184285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the influence of progression of atherosclerosis on clinical outcome in a cohort of 428 consecutive patients with isolated venous coronary artery bypass graft surgery followed prospectively for 15 years. In 189 patients 307 repeat coronary angiograms were performed because of recurrent signs of ischemia. Progression in the native coronary circulation only was found in 38 angiograms (12%), in both the native circulation and in venous grafts in 66 angiograms (21%), in venous grafts only in 135 angiograms (44%), and no progression was found in 68 angiograms (22%). In all the angiographies with a proven progression in the native coronary arteries, 40% was found to be distal to a vein graft insertion. In multivariate analysis the number of distal anastomoses predicts progression in both the native circulation and in venous grafts. Thus, progression is determined by the extensiveness of coronary artery disease at operation. Also, the interval between operation and repeat angiography predicts progression in the native circulation. We conclude that clinical outcome is also determined by progression in the native coronary circulation. Secondary prevention may, therefore, benefit not only the long-term result in patients with venous bypass grafts but probably also in patients with any type of coronary bypass surgery. |
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Authors:
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B L van Brussel; H W Plokker; A A Voors; S M Ernst; H C Kelder |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Catheterization and cardiovascular diagnosis Volume: 41 ISSN: 0098-6569 ISO Abbreviation: Cathet Cardiovasc Diagn Publication Date: 1997 Jun |
Date Detail:
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Created Date: 1997-07-29 Completed Date: 1997-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7508512 Medline TA: Cathet Cardiovasc Diagn Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 141-50 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Diaconessenhuis, Eindhoven, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arteriosclerosis
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etiology*,
physiopathology Coronary Artery Bypass / adverse effects* Female Follow-Up Studies Humans Male Middle Aged Multivariate Analysis Risk Factors |
| Comments/Corrections | |
Comment In:
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Cathet Cardiovasc Diagn. 1997 Jun;41(2):151
[PMID:
9184286
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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