Document Detail

Progress in measurement instruments for acute and chronic gout studies.
MedLine Citation:
PMID:  19820224     Owner:  NLM     Status:  MEDLINE    
Consensus exercises have identified and prioritized domains of measurement for studies in acute and chronic gout. In parallel, the technical properties of instruments for measurement in many of these domains have been assessed, with the main objective to consider the instruments in the context of the OMERACT filter of truth, discrimination, and feasibility. These data were presented and discussed at OMERACT 9 in the gout workshop, in breakout groups, and at informal meetings of the gout group. In acute gout, instruments for domains of pain, joint swelling, joint tenderness, and patient and physician global assessment have been assessed. In chronic gout, some validation exercises have been performed in instruments for domains serum urate, tophus measurement, health-related quality of life (HRQOL). In voting at OMERACT 9, the Medical Outcomes Study Short-Form 36 was endorsed as a valid instrument for measurement of HRQOL. Methods of tophus measurement were considered to have met some criteria of the OMERACT filter, but these require further work, particularly regarding sensitivity to change over shorter time periods. Priorities for future research include measurement of joint inflammation in acute gout and disability in acute and chronic gout.
Rebecca Grainger; William J Taylor; Nicola Dalbeth; Fernando Perez-Ruiz; Jasvinder A Singh; Royce W Waltrip; Naomi Schlesinger; Robert Evans; N Lawrence Edwards; Francisca Sivera; Cesar Diaz-Torne; Patricia A MacDonald; Fiona M McQueen; H Ralph Schumacher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  36     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-12     Completed Date:  2010-02-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  2346-55     Citation Subset:  IM    
Department of Medicine, University of Otago, and the Malaghan Institute of Medical Research, Wellington 6242, New Zealand.
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MeSH Terms
Acute Disease
Arthralgia / physiopathology
Chronic Disease
Consensus Development Conferences as Topic
Disability Evaluation
Gout / diagnosis*,  physiopathology,  psychology
Outcome Assessment (Health Care) / methods*,  trends*
Quality of Life
Severity of Illness Index*
Uric Acid / blood
Reg. No./Substance:
69-93-2/Uric Acid

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