| Progress in investigating the pathogenesis of hepatopulmonary syndrome. | |
| | |
MedLine Citation:
|
PMID: 20688597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The pathogenesis of hepatopulmonary syndrome is complicated and remains unknown. This review aims to provide an updated knowledge about the pathogenesis of the syndrome. DATA SOURCES: Five medical databases, MEDLINE, ScienceDirect, OVID, Springer Link, and Wiley InterScience were searched for articles on "hepatopulmonary syndrome", "cirrhosis", "angiogenesis", "intestinal endotoxemia", "nitric oxide", "carbon monoxide", and other related subjects. RESULTS: Currently, imbalance between vasodilation and vasoconstriction, intestinal bacterial translocation, intestinal endotoxemia, and activation of the lung monocyte/macrophage system may play important roles in the pathogenesis of hepatopulmonary syndrome. Recent studies found that angiogenesis is also an important factor in the pathogenesis of experimental hepatopulmonary syndrome. CONCLUSION: Angiogenesis inhibition may be a potential approach for the treatment of hepatopulmonary syndrome in the future. |
| | |
Authors:
|
Zhao-Jie Zhang; Chang-Qing Yang |
Related Documents
:
|
9188667 - Intestinal malrotation in a child with cardio-facio-cutaneous syndrome. 10569507 - Failure to pass meconium: diagnosing neonatal intestinal obstruction. 705537 - Vipomas and the watery diarrhoea syndrome. 15581837 - Non-lethal hallermann-streiff syndrome with bone fracture: report of a case. 1456287 - Long-term evaluation of a child with the branchio-oculo-facial syndrome. 7575067 - Adult hemolytic-uremic syndrome. a review of 37 cases. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Hepatobiliary & pancreatic diseases international : HBPD INT Volume: 9 ISSN: 1499-3872 ISO Abbreviation: HBPD INT Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-08-06 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101151457 Medline TA: Hepatobiliary Pancreat Dis Int Country: China |
Other Details:
|
Languages: eng Pagination: 355-60 Citation Subset: IM |
Affiliation:
|
Institute of Digestive Diseases, Tongji Hospital, Tongji University School of Medicine, Shanghai, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Endotoxemia
/
physiopathology Hepatopulmonary Syndrome / etiology*, physiopathology* Humans Lung / pathology Neovascularization, Pathologic / physiopathology Vasoconstriction / physiology Vasodilation / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Outcomes and mechanisms of ischemic preconditioning in liver transplantation.
Next Document: Radiofrequency ablation, heat shock protein 70 and potential anti-tumor immunity in hepatic and panc...