| Progress in diagnosis of hepatitis and the cirrhotic liver. | |
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MedLine Citation:
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PMID: 10219695 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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History of the concept and definition of hepatitis is briefly reviewed. The landmarks of progress are based on better understanding of liver structure and introduction of biopsy techniques to follow the pathologic alterations in acute and chronic hepatitis, cirrhosis, dysplasia and hepatoma. Modern achievements are recognition of the etiologic agents of viral hepatitis A through G, viral nucleic acid sequencing, viral genome and gene products leading to development of immunologic tests to etiologic diagnosis. Viral particles are visualized by electron microscopy. In tissue, localization of viral products is obtained by histochemical, immunologic and by in situ hybridization methods. Diagnostic criteria for each of the viral etiologic agents is reviewed, as is cirrhosis and its occurrence in viral hepatitis and alcohol abuse. |
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Authors:
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J G Szakacs; J E Szakacs |
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Publication Detail:
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Type: Historical Article; Journal Article |
Journal Detail:
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Title: Annals of clinical and laboratory science Volume: 29 ISSN: 0091-7370 ISO Abbreviation: Ann. Clin. Lab. Sci. Publication Date: 1999 Apr-Jun |
Date Detail:
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Created Date: 1999-06-16 Completed Date: 1999-06-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0410247 Medline TA: Ann Clin Lab Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 87-103 Citation Subset: IM; Q |
Affiliation:
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Department of Pathology, Salt Lake City VAMC, UT 84148, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Hepatitis
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diagnosis,
history* Hepatitis, Autoimmune / diagnosis, history Hepatitis, Viral, Human / diagnosis, history History, 17th Century History, 18th Century History, 19th Century History, 20th Century History, Ancient Humans Liver Cirrhosis / diagnosis, history* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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