| Progress in depsipeptide-based biomaterials. | |
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MedLine Citation:
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PMID: 20602421 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polydepsipeptides - alternating copolymers of an alpha-amino acid and an alpha-hydroxy acid - are a group of biodegradable polymers. Versatile polydepsipeptides with or without pendant functional groups, as well as various polymer architectures, for example, providing alternative, random, diblock, triblock, multiblock or graft sequence structures, can be synthesized via ring-opening copolymerization of various morpholine-2,5-dione derivatives. They are potential candidates for a wide range of biomedical applications. Polydepsipeptides are described in this review from the aspect of materials science, especially as biomaterials. We mainly focus on various techniques developed to synthesize polydepsipeptides and their copolymers, biodegradation behaviors, shape-memory properties and possible biomedical applications. |
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Authors:
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Yakai Feng; Jian Lu; Marc Behl; Andreas Lendlein |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Macromolecular bioscience Volume: 10 ISSN: 1616-5195 ISO Abbreviation: Macromol Biosci Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-02 Completed Date: 2010-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101135941 Medline TA: Macromol Biosci Country: Germany |
Other Details:
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Languages: eng Pagination: 1008-21 Citation Subset: IM |
Affiliation:
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School of Chemical Engineering and Technology, Tianjin University, Weijin Road 92, 300072 Tianjin, China. yakaifeng@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials
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chemistry* Depsipeptides / chemistry*, therapeutic use Polymers |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/Depsipeptides; 0/Polymers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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