| Progress on the screening and analysis of bioactive compounds in traditional chinese medicines by biological fingerprinting analysis. | |
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MedLine Citation:
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PMID: 20883192 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Traditional Chinese medicines (TCMs), a key branch of natural medicines, play an important role in treatment of diseases because of their reliable clinical performance. Identification of their active compounds constitutes a bottleneck in the development of TCMs. Screening and analysis of active compounds is a challenge in TCMs research. This review summarizes recent progress in the development of biological fingerprinting strategies for screening and analyzing of bioactive compounds in TCMs using molecular recognition, metabolism and omics tools.The evaluated strategies including the following techniques: microdialysis/centrifugal ultrafiltration-HPLC, biochromatography, metabolic fingerprinting analysis, 2-dimensional biochromatography and omics fingerprinting analysis. |
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Authors:
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Fengjiao Yu; Liang Kong; Hanfa Zou; Xiaoyuan Lei |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Combinatorial chemistry & high throughput screening Volume: 13 ISSN: 1875-5402 ISO Abbreviation: Comb. Chem. High Throughput Screen. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9810948 Medline TA: Comb Chem High Throughput Screen Country: Netherlands |
Other Details:
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Languages: eng Pagination: 855-68 Citation Subset: IM |
Affiliation:
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Key Laboratory of Offshore Marine Environment Research of Liaoning Higher Education, Dalian Ocean University, Dalian, 116023, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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