Document Detail

Prognostic value of vocal cord fixation with respect to treatment in cancers of the supraglottis and pyriform sinus.
MedLine Citation:
PMID:  3683056     Owner:  NLM     Status:  MEDLINE    
Vocal cord fixation in supraglottic and pyriform sinus cancers has, in the past, precluded management by radiotherapy alone. Ninety-eight patients were reviewed to determine the prognostic effect of vocal cord fixation. The predictive value of cord mobility status after 50 Gy was evaluated with respect to treatment modality. For patients treated with radiotherapy alone, cord mobility status was predictive of recurrence, yielding 3 year recurrence rates of 33.3% (mobile) versus 80% (fixed) [p = 0.04]. Mobile cords after 50 Gy had similar recurrence rates (33.3% vs. 40.0%, p = 0.60) whether treated by radiotherapy or radiotherapy/surgery. Radiotherapy alone may be used in cases when fixed cords become mobile after 50 Gy without compromising cure rates or laryngeal function. Combined modality provides the best results when cords remain fixed.
C A Spaulding; A Gillenwater; W C Constable; S S Hahn; C R Kersh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  97     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-05     Completed Date:  1988-01-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1450-3     Citation Subset:  IM    
Division of Radiation Oncology, University of Virginia Medical Center, Charlottesville 22908.
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MeSH Terms
Aged, 80 and over
Combined Modality Therapy
Laryngeal Neoplasms / complications*,  physiopathology,  radiotherapy,  surgery
Middle Aged
Pharyngeal Neoplasms / complications*,  physiopathology,  radiotherapy,  surgery
Vocal Cord Paralysis / etiology*
Vocal Cords / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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