Document Detail


Prognostic value of systolic ankle and toe blood pressure levels in outcome of diabetic foot ulcer.
MedLine Citation:
PMID:  2731457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prognostic value of distal blood pressure measurements has been studied in 314 consecutive diabetic patients with foot ulcers. Systolic toe blood pressure was measured with a strain-gauge technique, and ankle pressure was measured with strain-gauge or Doppler techniques. Wound healing was defined as intact skin for at least 6 mo. One hundred ninety-seven patients healed primarily, 77 had amputations, and 40 died before healing had occurred. In 294 of 300 patients, it was possible to measure either ankle or toe pressure. Fourteen patients were not available for pressure measurements. Of these, 10 patients healed primarily, and 4 died before healing occurred. Both ankle and toe pressures were higher (P less than .001) among patients who healed without amputation compared with those who underwent amputation or died before healing. No differences were seen in ankle or toe pressure levels among those who had amputations or died. No patient healed primarily with an ankle pressure less than 40 mmHg. An upper limit above which amputation was not required could not be defined. Primary healing was achieved in 139 of 164 patients (85%) with a toe pressure level greater than 45 mmHg, whereas 43 of 117 patients (36%; P less than .001) healed without amputation when toe pressure was less than or equal to 45 mmHg. In conclusion, a combination of ankle and toe pressure measurements is a useful tool to predict primary healing in diabetic foot ulcers.
Authors:
J Apelqvist; J Castenfors; J Larsson; A Stenström; C D Agardh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes care     Volume:  12     ISSN:  0149-5992     ISO Abbreviation:  Diabetes Care     Publication Date:  1989 Jun 
Date Detail:
Created Date:  1989-07-21     Completed Date:  1989-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805975     Medline TA:  Diabetes Care     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  373-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University Hospital, Lund, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Aged
Amputation
Ankle
Diabetes Complications*
Diabetes Mellitus / physiopathology
Diabetic Neuropathies / physiopathology
Female
Foot Diseases / physiopathology*
Humans
Male
Middle Aged
Myocardial Contraction*
Prognosis
Prospective Studies
Skin Ulcer / physiopathology*
Systole*
Toes
Ultrasonics
Wound Healing*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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