Document Detail


Prognostic value of preoperative C-reactive protein concentration and white cell count in acute extremity ischaemia.
MedLine Citation:
PMID:  7662777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To find out if the C-reactive protein (CRP) concentration and the white cell count (WCC) are of any prognostic value in patients with acute extremity ischaemia. DESIGN: Retrospective study. SETTING: Tampere University Hospital and Jyväskylä Central Hospital, Finland. SUBJECTS: 129 patients with acute extremity ischaemia. MAIN OUTCOME MEASURES: Preoperative CRP concentration, white cell count, packed cell volume, serum creatinine concentration, major amputation and death. RESULTS: The median (range) CRP concentration was 50.0 (3-271) mg/l in the 28 patients who underwent major amputation or died (group 1) and 11.0 (1.175) mg/l in the 65 patients who survived with viable limbs (group 2) (p = 0.007). The median (range) WCC was 13.1 (5.9-42.0) x 10(9)/l in group 1 (30 patients) and 9.5 (2.2-23.9) x 10(9)/l in group 2 (79 patients) (p < 0.001). The cut-off point of 20 mg/l for CRP and 11.0 x 10(9)/l for WCC had negative predictive values of 0.83 and 0.85 for amputation and mortality, respectively. CONCLUSION: Preoperative CRP concentration and WCC correlated with limb salvage and mortality in patients with acute extremity ischaemia.
Authors:
P Kuukasjärvi; J P Salenius; H Riekkinen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The European journal of surgery = Acta chirurgica     Volume:  161     ISSN:  1102-4151     ISO Abbreviation:  Eur J Surg     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-10-10     Completed Date:  1995-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105264     Medline TA:  Eur J Surg     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  335-9     Citation Subset:  IM    
Affiliation:
Department of Surgery, Tampere University Hospital, Finland.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Aged
Aged, 80 and over
C-Reactive Protein / analysis*
Extremities / blood supply*
Female
Humans
Ischemia / blood*
Leukocyte Count*
Male
Middle Aged
Predictive Value of Tests
Preoperative Care
Prognosis
Retrospective Studies
Chemical
Reg. No./Substance:
9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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