Document Detail


Prognostic value of positive pleural lavage in patients with lung cancer resection.
MedLine Citation:
PMID:  10355426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Despite an early stage, lung cancer patients often have a poor survival, suggesting inaccurate staging. A pleural lavage demonstrating malignant cells at the time of operation may predict a poorer survival, particularly in patients with otherwise early disease. METHODS: Patients, with no preoperative evidence of pleural effusions and undergoing a surgical resection with curative intent, had a preresectional and postresectional lavage to be evaluated by cytology. RESULTS: Fourteen percent of patients with stage I disease had malignant cells in their preresectional lavage and had a significantly shorter survival than stage I patients with a negative lavage. Positivity of preresectional lavage was not correlated with nodal status, pleural or lymphatic involvement, or histologic findings. CONCLUSIONS: Preoperative pleural lavage should become a standard technique intraoperatively to better characterize and stage patients undergoing lung cancer resections. Patients with malignant cells in their preoperative lavage should be upstaged.
Authors:
C M Dresler; C Fratelli; J Babb
Related Documents :
15276856 - Development of pericardial mesothelioma in golden retrievers with a long-term history o...
12411036 - Clinical analysis of 4 cases of juvenile granulosa cell tumor of the ovary.
20103236 - Second surgery for recurrence of malignant pleural mesothelioma after extrapleural pneu...
17484626 - Mesothelin family proteins and diagnosis of mesothelioma: analytical evaluation of an a...
15127156 - Prognostic factors for brain metastases after whole brain radiotherapy. data from a sin...
11505486 - Cancer of retromolar trigone: long-term radiation therapy outcome.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  67     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-06-23     Completed Date:  1999-06-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1435-9     Citation Subset:  AIM; IM    
Affiliation:
Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / mortality,  pathology*,  surgery
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell / mortality,  pathology*,  surgery
Female
Humans
Intraoperative Period
Irrigation
Lung Neoplasms / mortality,  pathology*,  surgery
Male
Middle Aged
Neoplasm Staging
Pleural Effusion, Malignant / pathology*
Pneumonectomy
Prognosis
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Reduced neutrophil infiltration protects against lung reperfusion injury after transplantation.
Next Document:  Initial experience with two sequential anterolateral thoracotomies for bilateral lung transplantatio...