Document Detail


Prognostic value of pharmacological stress echocardiography in diabetic patients.
MedLine Citation:
PMID:  12928024     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our study was undertaken to assess the prognostic significance of pharmacological stress echocardiography in 325 diabetic patients. Pharmacological stress echocardiography was performed for diagnosis of coronary artery disease in 128 patients, and for risk stratification in 197 patients. Follow-up was 34 months. Cardiac-related death and non-fatal myocardial infarction were considered hard events. During the follow-up period, there were 38 deaths and 23 acute non-fatal myocardial infarctions. By univariate analysis, a pharmacological stress echocardiography positive response for ischaemia indicated an increased risk of cardiovascular death. However, by multivariate analysis, advanced age and peak ejection fraction <40% were the only independent predictors of cardiac death. The same peak ejection fraction (EF) <40%, rest wall motion score index and previous myocardial infarction were independent predictors of hard events. After dividing the population into two subgroups on the basis of EF at rest, only a peak EF <40% and a pharmacological stress echocardiography positive test were powerful independent predictors of cardiovascular mortality.
Authors:
A D'Andrea; S Severino; P Caso; L De Simone; B Liccardo; A Forni; M Pascotto; G Di Salvo; M Scherillo; N Mininni; R Calabrò
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  4     ISSN:  1525-2167     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-20     Completed Date:  2003-12-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  202-8     Citation Subset:  IM    
Affiliation:
Medical-Surgical Physiopathology of Cardiopulmunar and Respiratory System and Associated Biotechnologies, Second University of Naples, Corsa Europa 72, Naples, Italy. adandrea@synapsis.it
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Agonists / administration & dosage,  diagnostic use
Aged
Angioplasty, Transluminal, Percutaneous Coronary
Cohort Studies
Coronary Artery Bypass
Diabetes Mellitus / diagnosis*,  epidemiology
Dipyridamole / administration & dosage,  diagnostic use
Dobutamine / administration & dosage,  diagnostic use
Echocardiography, Stress*
Electrocardiography
Female
Follow-Up Studies
Heart Ventricles / physiopathology,  ultrasonography
Humans
Male
Middle Aged
Multivariate Analysis
Myocardial Ischemia / diagnosis,  epidemiology,  therapy
Observer Variation
Predictive Value of Tests
Prognosis
Risk Factors
Statistics as Topic
Stroke Volume / physiology
Survival Analysis
Systole / physiology
Treatment Outcome
Vasodilator Agents / administration & dosage,  diagnostic use
Ventricular Dysfunction, Left / diagnosis,  epidemiology,  therapy
Chemical
Reg. No./Substance:
0/Adrenergic beta-Agonists; 0/Vasodilator Agents; 34368-04-2/Dobutamine; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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