Document Detail

Prognostic value of the metabolic syndrome for long-term outcomes in patients undergoing percutaneous coronary intervention.
MedLine Citation:
PMID:  17127794     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The prevalence of metabolic syndrome (MS), regarded as an important risk factor for coronary artery disease, is growing. However, the relationship between MS and long-term outcomes after percutaneous coronary intervention (PCI) in the Japanese patient population remains unknown. METHODS AND RESULTS: Seven-hundred and forty-eight consecutive patients who underwent PCI were assessed. Patients were categorized by the presence or absence of MS using the NCEP-ATPIII definition (for obesity, a body mass index >or=25 kg/m(2) was used). Kaplan-Meier estimation and Cox proportional hazards model were used for unadjusted and adjusted analyses for all cause mortality and cardiac events. The progress of 318 (42.5%) patients with MS and 430 (57.5%) patients without MS was analyzed. The mean follow-up was 12.0+/-3.6 years. Overall, there were 88 (11.8%) deaths from all causes, and there were no significant differences between the 2 groups. The occurrence of cardiac events was significantly higher in the MS group than that in the no MS group (25.5% vs 15.6%, hazard ratio 2.23; 95% confidence interval 1.59-3.11; p<0.001). CONCLUSIONS: The presence of MS significantly increased the risks of subsequent cardiac events among patients who underwent PCI.
Takatoshi Kasai; Katsumi Miyauchi; Takeshi Kurata; Hiroshi Ohta; Shinya Okazaki; Tetsuro Miyazaki; Kan Kajimoto; Naozumi Kubota; Hiroyuki Daida
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  70     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-27     Completed Date:  2007-01-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1531-7     Citation Subset:  IM    
Department of Cardiology, Juntendo University, School of Medicine, Tokyo, Japan.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Asian Continental Ancestry Group
Body Mass Index
Coronary Artery Disease / complications,  mortality,  therapy*
Metabolic Syndrome X / complications*,  epidemiology,  mortality
Middle Aged
Myocardial Ischemia / complications,  epidemiology
Treatment Outcome

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